Hollywood actor Eric Dane shared an emotional Instagram video on September 15, 2025, marking his partnership with the I Am ALS organization. Fans quickly noticed visible changes in his speech and movements, commenting on his “slurred” voice and “twitching” muscles. The post came months after Dane revealed his ALS diagnosis in April and following his absence from the 2025 Emmy Awards, where he was set to celebrate Grey’s Anatomy’s 20th anniversary.

In the video, Dane introduced himself simply: “I’m Eric. An actor, a father, and now a person living with ALS.” He urged viewers to take action against a disease that remains incurable despite decades of research.

Dane promoted Push for Progress, I Am ALS’s ambitious campaign to raise $1 billion within three years to accelerate treatment development, expand access to care, and modernize ALS legislation.

He also shared details of his personal journey, recalling early symptoms like weakness in his right hand and a frightening boating incident when his youngest daughter helped him to safety.

Despite these challenges, Dane expressed deep gratitude toward his wife, Rebecca Gayheart, and their teenage daughters, saying their love and strength had brought the family even closer together.

“I don’t think this is the end of my story,” he said. “I’m fighting as much as I can.” Acting, he explained, continues to be a lifeline that keeps his mind sharp and gives him a sense of purpose.

Fans praised his honesty and courage, flooding the comments with messages of support and admiration.

Now, Eric Dane stands not just as a Hollywood star but as a powerful advocate and symbol of resilience—using his platform to inspire others and shed light on ALS, reminding the world that determination and hope can shine even in life’s darkest moments.